Thursday, January 29, 2009
kicks and giggles
oh my god, i forgot my mustache!
quiero tener una coca cola contigo.
let's just tell everyone we blew the circut because we had four microwaves and the vacuum plugged in.
can we just lock the doors and go home early?
Wednesday, January 28, 2009
the color blue
the second note: i'm really quite proud of myself for keeping up with this all week
i know that the purpose of these blogs isn't to be a here's what happened to me today story but i'm going to break that rule today and tell all maybe five of you about my day. so this morning i was running kinda behind just a bit. but that's okay because i give myself about 10 minutes of extra time so that when i do run late i make it to school on time still. i don't like arriving late, it bugs me. but that's not important. i pull into the south lot and park my car in the usual row and then wait to exit my car while a car pulls in next to me. of course i glance up to see who it is and i don't recognize him. i gather all my stuff and then brace myself for the chilly walk to the school. we both leave our cars and then speed walk to the school. he either gets cold easily or just walks super fast and was soon a little ahead of me. i'm thinking this is nothing out of the ordinary, just because i go to school with this guy doesn't mean i'm going to talk to him as we walk to the school. i don't even know who he was. but when i get up to the school i see him walk up to the door and then hold it open for me. and it wasn't one of those hold it open from the inside until i grab the door things it was the all out he stood outside and held the door open for me. i said smiled and said thank you. he replied with a you're welcome and a smile as well. we went our separate ways and i still have no idea who he is. for the purpose of this i'm going to call him...jim.
today jim kinda renewed my faith in humanity. he showed me that not everyone is wrapped up in their own lives and that people out there still are willing to lend a helping hand, even if it's to a perfect stranger. so what did i do? i paid it forward and lent a helping hand today. the wind symphony traveled to one of the area middle schools today to play a recruiting concert. while walking to the car of the band mommy i was riding with i see the string base player trying to get his monstrously big instrument into the back of his truck. it was one of those trucks with the cover things making it not really a truck and, wow i'm not good at explaining cars so bear with me here, the window that is actually like a door didn't want to stay open and was causing troubles with the whole getting the big string bass into the bed of his truck that isn't actually a truck. so i held it open for him. he got the string bass in, smiled and said thanks. i played the part of jim, smiled back and said you're welcome.
Tuesday, January 27, 2009
life as i see it
forget regrets or life is yours to miss --RENT
Monday, January 26, 2009
siiick
i try not to miss school for being sick because two days worth of homework and then having to make up any tests or quizzes only puts more strain on me. it's kind of a sad story. but hey, maybe i'll think of something else to blog about and then i'll have two of my three posts for the week done. let's not get too far ahead of myself now. i probably shouldn't even count this as one seeing as how it's not even going to be half of the required amount.
Sunday, January 25, 2009
jefferson: please stop trying
this has no point what so ever.
i tried to put a picture into that last post. as you can tell, it didn't work. i forgot how to. but it was supposed to be of the green m&m lady. yes, i know, green m&m lady and valentine's day don't really correspond but if you ate lunch at my table in eighth grade you would understand.
secret secret, i got a secret. mr. roboto anyone? did you get it? it's okay if you didn't. but anyways, a secret is a secret and they should probably be kept. especially if you say you're not going to tell anyone. your friends won't like you very much if you fail at keeping secrets. but whatever, you do what you want because it's your life.
elf! i love, love, love elf. because we have it in the break room at work i'm working on memorizing it, but not line for line because i don't work that much. [nor do i want to] but i am getting pretty good at quoting some of the major parts of the movie. like this one for example "SANTA'S COMING?!? I KNOW HIM!!!!!!!!" and my personal favorite "you're not santa, you stink. you smell like beef and cheese. pulls off fake beard and a fight then ensues." i love elf.
obama is officially president. i do kinda feel bad for him though, everyone is expecting him to fix everything. that's a lot of cleaning to do, it's kinda a big mess out there. so, good luck mr. president, i'm rooting for you.
lookey there, i figured out how to change the font size. yay me. too bad i'm still fifty words away from the assigned number. boo expectations.
so to make it to the expected number i'll leave you with a list of things
- i don't like monday mornings.
- or sunday nights for that matter either.
- school and homework take up far too much of my time.
- pep band ruins my friday nights, but i would rather go on a friday night than a tuesday
- i think i might go crazy next year
- i'm running out of things to say
- my car always needs gas and i never want to get it.
- only some of these things have periods others are left without punctuation
- i still have some uncompleted assignments that are due tomorrow.
- i don't plan on doing most of them.
- don't worry mr. ayers, i'll write my final draft.
- i'm not a big fan of other people's feet.
- i get cold really easily.
- i like making this list.
- i love all my friends and i'll love them forever
- next week is winter spirit week.
- i don't like winter, so i don't plan on participating.
- monday's theme is career day, i spun the spinner one of my friends made and i'm supposed to dress up like a mail lady. not going to.
- i guess i'm no fun. but i don't like winter so i'm not participating.
i'm done spewing randomness now.
holidays. continued?
as i walk into my dentist office on january 19th i see pink and red everywhere. and hearts and balloons. and twirly things hanging from the ceiling. one of those banners where all the letters are connected reads happy valentine's day! it's january 19th. basically a month away, and my dentist is already celebrating. they even gave us wonderfully sugar coated cookies as we walked out the door. shaped in a heart of course with a heart shape in the frosting as well. i don't know how most people view valentine's day, but to me it's not really worth a whole month of preperation. sure you get all the warm fuzzies as you spend your day with those closest to you all that jazz, but really? a whole month ahead of time? kinda makes it seem like february 14th is going to be the best day of the year. maybe it is to some.
after working in retail over the holiday season i have come to this conclusion: america over celebrates the holidays. as soon as halloween ended we were preparing for thanksgiving and as soon as thanksgiving ended up came the christmas trees. is our world really that bad that we need to look so far ahead to find something worth celebrating? i sure hope not. celebrate the small stuff, don't take it forgranted.
Thursday, January 22, 2009
microbes...!
"Chapter five talks about microbes, more specifically host manipulating microbes! The nasty human affecting microbe, the Guinea worm is one crafty little guy. You’re only at risk if you spend a lot of time with contaminated water so we should all be good, but if you get one it lives inside you and grows to about, oh, three feet long. Then its actions make you think that it’s decided that you’re no longer a good enough host and wants to come out. It does this by giving you painful blisters that burn with a fiery sensation so you automatically think, okay let’s just submerge my arm in some nice cool water. DON’T DO IT!! By submerging you arm in water the little Guniea worm let’s all of its little babies out into you. So now instead of having just one wormy living inside you, you have many, many, many. The only good way, that’s been found, of getting them out is wrapping them around something like a toothpick and slowly pulling them out bit by bit. Unfortunately this usually takes more than one day. Just one more host manipulator microbe example is the Dicrocelium Dentriticum. Basically, it’s a parasite that lives in sheep, but the thing is that it uses ants as a Trojan horse to get into the sheep. These little guys mess with the brains of the ants making them suicidal; once affected the ants go hang out on the ends of the blades of grass just hoping to be eaten by a sheep."
there's also one more type of microbe mentioned in the book that i didn't put in my book report and it's the Hymenoepimecis argyraphaga. because no one in their right mind knows what that is, i will call it the parasitic wasp that messes with the mind of Plesiometa Argyra, a spider. this spider is just a minding it's own business weaving its orb shaped webs all over the places in hopes of catching the little bug that blindly walks into in and then becomes lunch. to rain on this nice little parade, out of nowhere comes the parasitic wasp and he/she stings the spider. okay it's a she, because when she stings the poor little spider she deposits her eggs in it. after a short stint of being paralyzed by the sting from the evil wasp, spider wakes back up and goes about his/her business not knowing that his/her days are numbered. all the little wasp eggs living in the spider soon hatch into little wasp larva, and they're hungry. so what do they do? they suck the blood of the spider but for some reason the spider can't feel it so it just keeps on spinning webs. once this gets boring for the larva and they decide it's time to cocoon they inject some chemicals into the head of the spider. so now the spider is all drugged up and can only remember how to do steps on and two of its web making. after repeating steps one and two about fourty times, and this usually happens at midnight, the spider just stops. no more movement from mr. spider. the larva then kill motionless mr. spider and use the product of repeating steps one and two fourty times to have a nice place to hang it cocoon from. give it a week or two and you now have some more wasps. nasty little guys aren't they.
Monday, January 19, 2009
so, where you going to go to school?
i kinda think i know where i want to go to school. but then i think to myself, how can i pick a school when i'm not sure what i want to do? i really can't. so right now the tentative ISU pick is just something i came up with, with basically no good reason to back it up. maybe i'll decided that i wanna go out of state. but probably not because out of state costs are horrible.
i have recently started to just throw out random majors when i'm asked what i want to do. it'll be a while before i see these people again and i hightly doubt they'll even remember what i told them last time. so then if i ever decide on what i'm actually going to major in i can tell them that one for real. recently i have been telling people that i'm planning on majoring in big smart sounding things like biochemistry. or bio medical engineering. or just plain medicine. or chemical engineering. or micro biology. seems like i really like biology? meh, i don't know.
Monday, January 12, 2009
the outside world
let's compare my box to um, i don't know, something that has many little boxes connected together. because i have other little boxes that i live in outside of my main brick covered box. this next box is a metal box. it's where i work. i don't live in this box very often. though i tend to enjoy it when i do, i actually like my job no matter how much i complain about it. i like the people i work with. we all like our metal box. it has a name too, old navy. then there are random other boxes that i visit from time to time.
so now that i've spent some time comparing my life to boxes i kinda feel like explaining why. here is why, we are extremely sheltered people. and by extremely sheltered i mean EXTREMELY SHELTERED. seriously, my idea of the outside world is anything outside my box. i think. okay, i'm pretty sure. i live in a world surrounded by these nice four walls. i rarely have to leave my world of boxes. a traumatizing story would fit nicely here but i don't have any.
i just wonder if my world of boxes is going to come with me when i move away and go to the wonderful world of college. i'm guessing that it probably will, and my green and gold brick colored box will probably change colors to show that of the school i'm now going to. //i still do not know where i'm going to college. i do not know when i will be deciding this// but i'm guessing that my box won't be as, i don't know, boxey? my new box probably won't be the sturdiest, it is closer to the outside world so there's a good chance that the cardboard won't be as thick. or maybe it'll be missing chunks in the sides. i don't know.
now that i have you all thinking i live in a carboard box i should probably end this post.
PDA
we all make fun of you in our classes. think of things to do to either make you stop or move away from our classroom so we don't have to see you every day. i really don't see why the teachers don't do anything about this. they complain about it right along with the students, yet they do nothing to try to put a stop to it.
i think we should all be able to have those little squirt bottles and a be able to shoot water at anyone we see making out. that would definitley brighten my day. too bad people would abuse this and just squirt whomever they wanted to.
it's not like this is the only time you are going to see each other, i'm sure you spend ample time together outside of school. so why don't you just wait until you're not surrounded by 1800 other people? i suggest doing that. you should try it, okay? okay good.
and today i did...
school seems to be kinda pointless to me these days. we do the same stuff in every class with the only difference being the subject material. homework is rarely ever checked for a grade and if it is checked it's checked for completion. meaning i can just scribble some stuff down and i get full credit. why did i have to even attempt at this, i know there are some kids in my class who wrote down nonsense, yet they're going to get the credit just because it's only for completion.
after taking a test i promptly forget everything i have just learned and i do not look at any past material until finals time. and then i only have to look at the main idea because so much is shoved onto those final tests that you can't really go into much depth on anything for fear of leaving out some other important topic. every class is the same song just a different verse.
Thursday, January 8, 2009
memorization
transcription is the synthesis of RNA, specifically mRNA under the direction of DNA.
translation is the synthesis of a polypeptide chain and it occurs under the direction of mRNA.
((the base sequence of mRNA is translated into the amino acid sequence of polypeptides at the ribosomes))
some stuff to keep in mind...
- DNA splits into two separate strands, the coding and template strand. the template strand provides the sequence of bases while the coding strand just kinda hangs out and sits there. the coding strand does do one thing though, it has the TATA box which shows the prompter where to attach and then start scanning for the start codon, AUG.
- a codon is an mRNA triplet written 5'-->3', AUG is the start codon. it codes for methionine. redendancy is when multiple codons code for the same amino acid and wobble is when the third nucleotide in the sequence doesn't matter.
specifics of transcription:
step 1. initiation: RNA polymerase II binds to the prompter (the TATA box on the coding strand) and begins to unwind the DNA. RNA poly II then initiates RNA synthesis by finding the start codon AUG.
step 2. elongation: RNA poly II moves downstream, continually unwinding the DNA and elongating the RNA transcript. the RNA transcript is built 5'-->3', which means the nucleotides are added to the 3' end. confusing, yes i know.
step 3. termination: RNA transcript is released and RNA poly II detaches from the DNA. elongation continues for a bit after RNA poly II transcribes the termination sequence.
RNA processing because the mRNA just transcribed is not yet good enough to be used for translation
- a 5' cap consisting of a modified guanine nucleotide is added to the 5' end of the pre-mRNA transcript. a poly A tail consisting of multiple adenine nucleotides is added to the 3' end. these caps serve three purposes. 1- they facilitate the export of the mRNA from the nucleus. 2- the protect the mRNA transcript from enzymes. 3- they aid in the ribosomal attachment of the 5' end.
the RNA still isn't ready, it now has to go through splicing. RNA splicing is the removal of the noncoding segments (introns) so that the transcript only contains the coding segments (exons). EXONS-GOOD. INTRONS-BAD. these nifty little things called snRNPs (snerps) are needed to remove the introns and then a snRNP and protein combo form a spliceosome form and they reattach the exons back together. then there are these ribozymes and they're just RNA molecules that act as proteins and i'm not really sure what purpose they serve. TADA YOU HAVE JUST COMPLETED TRANSCRIPTION. FEEL FREE TO MOVE ON TO TRANSLATION NOW.
some more stuff to keep in mind...
- in translation the cell is interpreting a gentic message from mRNA and using it to build a polypeptide chain. it's tRNA [transfer RNA] that is used to interpret the codons on the mRNA.
- anticodons are found on tRNA and they're complementary to the codons found on mRNA. this is how the tRNA knows which amino acid comes next in the sequence. the amino acids attach to the 3' end of the tRNA when it pulls them to the ribosome from the nucleus.
- a nifty little guy called aminoacyl-tRNA synthetase is what attaches the amino acids and little tRNAs together.
- ribosomes are made up of rRNA [ribosomal RNA]. they have three binding sites, the P site, the A site, and the E site. the P site holds the tRNA carrying the growing polypeptide chain. the A site holds the tRNA carrying the next amino acid. the E site discharges the tRNAs.
specifis of translation:
step 1. initiation: mRNA, tRNA (with the first amino acid in tow)and ribosomal subunits are brought together. the mRNA and tRNA are bound to the small ribosomal subunit and then scans downstream until the start codon (AUG) is found. transcription starts here.
step 2. elongation: amino acids added to the polypeptide chain one by one as tRNA anticodons match up to the mRNA codons. there are three steps within elongation: 1- codon recognition 2- peptide bond formation 3- translocation. elongation continues until the stop codon reaches the A site.
step 3. termination: UAG, UAA, and UGA are the stop codons. release factors bind to the stop codon, adding a water molecule to the polypeptide chain. this causes the peptide chain to be released.
AN EXTREMELY SHORT VERSION OF WHAT HAPPENS ALL IN FIVE STEPS
- RNA transcribed from DNA template
- pre-mRNA spliced and modified into mRNA (eukaryotes only)
- mRNA attaches to ribosome in preperation for translation
- amino acids attach to appropriate tRNA anticodon
- tRNAs and their amino acid meet the mRNA codons at the ribosome and polypeptide chain grows.
Monday, January 5, 2009
um, uh, so yeah
saying like can be compared to saying um, uh, so, yeah, and words like that; they're just filler words. our attempts at filling the silence while our brain is still thinking of what to say next. you should really stop and listen to your fellow classmates and hear what they're really saying. i betcha you will find that you hear a lot of likes, uhs, ums, and blah blah blah the list goes on and on, you all know what words i'm talking about.